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Common names: Bahupatra,
Bhuiamla. Botanical name: Phyllanthus niruri. Phyllanthus is
an herb found in central and southern India. It can grow from 3060
centimeters in height and blooms with many yellow flowers. Phyllanthus species
are also found in other countries, including China (e.g., Phyllanthus
urinaria), the Philippines, Cuba, Nigeria, and Guam. All parts of the plant are
used medicinally to treat hepatitis and pain .
Phyllanthus has been used in Ayurvedic
medicine for over 2,000 years and has a wide number of traditional uses
including internal use for jaundice, gonorrhea, frequent menstruation, and
diabetes and topical use as a poultice for skin ulcers, sores, swelling, and
itchiness. The young shoots of the plant are administered in the form of an
infusion for the treatment of chronic dysentery.
Active constituents: Phyllanthus
primarily contains lignans (e.g., phyllanthine and hypophyllanthine),
alkaloids, and flavonoids (e.g., quercetin).
Phyllanthus blocks DNA polymerase, the
enzyme needed for the hepatitis B virus to reproduce. In one study, 59% of
those infected with chronic viral hepatitis B lost one of the major blood
markers of HBV infection (e.g., hepatitis B surface antigen) after using 900 mg
of phyllanthus per day for 30 days. While clinical trials on the
effectiveness of phyllanthus for HBV have been mixed, the species P. urinaria
and P. niruri seem to work better than P. amarus. Clinical trials with
hepatitis B patients have used 9002,700 mg of phyllanthus per
day.
Research has used the powdered form of
phyllanthus ranging from 9002,700 mg per day for three months. No
side effects have been reported using phyllanthus as recommended in the amounts
above. At the time of writing, there were no well-known drug interactions
with phyllanthus.
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